The medication embossed with “54 411” is known as buprenorphine. It is available legally by prescription only and is commonly used for opioid dependence and chronic pain. The pill is white, round, and 10 mg in strength.
Buprenorphine is a synthetic (manufactured) opioid that works as a partial opioid agonist. Although buprenorphine has some mild analgesic properties, It is most often used in the U.S. to treat opioid dependence. As a result, people do not experience drug cravings or opioid withdrawal symptoms. They can also not get high on other opioids because buprenorphine blocks the corresponding receptors.
Buprenorphine, as opioid replacement therapy, is comparable in many ways to methadone, but there are also some significant differences between the two drugs that have led to buprenorphine’s increasing popularity. For example, health providers can prescribe buprenorphine in take-home doses, which is not the case for methadone. Also, Buprenorphine withdrawal symptoms are less severe than withdrawal symptoms from methadone.
Notably, buprenorphine doesn’t work well for everyone, and some individuals find using a methadone maintenance treatment program produces more benefits. However, most people who have used buprenorphine have found it an effective and tolerable treatment for opioid addiction.
How Does The 54 411 Pill Work?
Persons who have become dependent on opioids develop additional opioid receptors, and as a result, naturally occurring levels of opioids in the brain can’t activate these unessential receptors. When these remain vacant, withdrawal symptoms occur. Once people become dependent on opioids, they need a steady intake of these to keep withdrawal symptoms at bay.
However, buprenorphine can attach to the brain’s opioid receptors without inducing the sought-after “high” and side effects of other opioids. When used in sufficient doses, buprenorphine can bind to enough of these receptors to dramatically reduce withdrawal effects.
Of importance, buprenorphine is not a full opioid agonist like heroin, meaning it does not activate each opioid receptor completely. Instead, buprenorphine is a partial agonist, which means that although it can bind to each opioid receptor, it can only activate them just enough to mitigate cravings and withdrawal symptoms and not enough to result in feelings of euphoria.
Moreover, a person taking buprenorphine for opioid addiction will not encounter withdrawal symptoms and cravings to use opioids. Also, because buprenorphine effectively sates opioid receptors, attempting to take another opioid or opiate such as heroin will not lead to any noticeable effects.
Is Buprenorphine Safe?
Buprenorphine is widely considered to be much safer to use than methadone. As a partial opioid agonist, buprenorphine is only able to activate the brain’s opioid receptors partially. People using excessive doses of methadone or other full agonist opioids, such as heroin, are at a much higher risk for respiratory depression, coma, and death. But because buprenorphine can’t wholly activate the receptors, it can’t produce significant effects on the central nervous system.
What Are the Side Effects of Buprenorphine?
Most people tolerate buprenorphine very well, although the medication may have some side effects. Possible side effects include the following:
- Sexual dysfunction
- Stomach pain
Who Shouldn’t Use The 54 411 Pill?
Buprenorphine isn’t suitable for everyone. People with an extremely high tolerance for opioids may find that the medication, as only a partial agonist, does not offer sufficient reprieve from withdrawal symptoms. Regardless of their past history of opioid use, methadone can work for anybody.
Other reasons why buprenorphine might not be appropriate for some individuals include the following:
- Co-occurring use or abuse of alcohol or benzodiazepines (polydrug use)
- Low motivation or an inability to comply with take-home opioid medication prescriptions
- Severe mental health disorders
- Certain physical illnesses
How Long Does Buprenorphine Treatment Last?
The duration of treatment can vary considerably depending on the needs and wants of the individual and can range from just a few days to being prolonged indefinitely.
Buprenorphine is most often employed in one of the following ways: (1) as a part of a brief detox period to reduce the severity of withdrawal symptoms from full agonist opioids, and (2) in a long-term opiate replacement maintenance program.
Note: Individuals who take buprenorphine for more extended periods generally experience better outcomes.
Treatment for Opioid Addiction
Buprenorphine products should only be used as part of a broader, more comprehensive treatment program administered by addicted professionals consisting of behavioral therapy, counseling, group support, and aftercare planning.
Just Believe Detox and Just Believe Recovery offer treatment for opioid abuse, dependence, and addiction. Our skilled, highly specialized staff are dedicated to ensuring those we treat receive the very best care, support, and education they need to recover and enjoy long-lasting sobriety and wellness!