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Trazodone (Pliva 433): Uses, Effects, and Abuse

Facts About Trazodone (Pliva 433) | Just Believe Recovery
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It is sometimes found as a white round pill, embossed with PLIVA 433 with a single center perforation for dividing in half. It is a 50mg tablet manufactured by Major Pharmaceuticals. Trazodone hydrochloride is an antidepressant drug that is used off-label for a variety of other purposes.

While this drug’s primary mechanism of action is not yet entirely understood, it is believed to attach to brain neurochemicals such as serotonin that inhibit reuptake or reabsorption. As a result, it can reduce depression symptoms, boost mood, increase appetite, and counteract anxiety symptoms when they occur.

Trazodone and Depression Treatment

Trazodone is primarily used to treat major depression, which is considered a mental health condition that can be treated. Clinical depression is characterized by a period of profound sadness, low motivation levels, and irritability lasting for at least two weeks in a row.

In these cases, the person’s depression becomes so severe that it is adversely affecting daily activities, and the person cannot function normally. According to various studies, a brain chemical imbalance is one of the causes of depression and one of the reasons why medications like trazodone are recommended to people to modulate these brain chemicals.

Trazodone Can Help With Sleep Disorders

Another common purpose for trazodone is to treat the symptoms of sleep disorders, such as insomnia. The primary reason for this is because when using trazodone, a common side effect is drowsiness. This is the reason why many individuals utilize trazodone as a sleeping pill substitute.

Also, trazodone may be prescribed to individuals in recovery who are experiencing insomnia as a part of withdrawal symptoms from more potent and addictive substances, such as opioids or alcohol.

However, it is essential to note that using this drug as a sleep aid is not a purpose approved by the Food and Drug Administration (FDA). Therefore, the number of studies on whether this drug is undoubtedly effective for insomnia and safe for use is scant.

Trazodone Can Help With Anxiety and Schizophrenia

Aside from treating depression and sleep problems, trazodone is also given as treatment to patients suffering from schizophrenia and anxiety disorder. Trazodone does not cure these two disorders, and instead, the drug only helps manage the underlying symptoms.

Side Effects

Aside from feeling drowsy, trazodone’s common side effects include the following:

  • Muscle pain
  • Constipation
  • Dry mouth or foul taste
  • Headaches
  • Weakness
  • Intense nightmares

In addition, some people also experience the following:

  • Hives and itchiness
  • Swelling
  • Sweating
  • Dizziness
  • Nausea
  • Diarrhea
  • Numbness
  • Reduced blood pressure
  • Tinnitus
  • Abnormal bruising/bleeding

Facts About Trazodone (Pliva 433) | Just Believe Recovery

Another known side effect of trazodone use is a condition known as priapism, which is hallmarked by a prolonged and painful penile erection that can last several hours—even if not actively engaging in sexual activity.

Although it may at first seem less-than-problematic that the drug is providing Viagra-like symptoms, priapism can result in permanent erectile dysfunction if it is not correctly attended medically. In addition, some people reported that they experienced decreased sexual drive while taking the drug.

Trazodone Warnings

People who experience heart conditions and older persons should be cautious about using this drug. Furthermore, it is not recommended for people with low magnesium and potassium levels in their blood. In addition, before using trazodone, individuals should consider what other drugs and substances they are taking as it can have interactions with several medications.

Also, while this medication can help treat major depressive disorder, a risk associated with taking it is suicidal ideations. This is because research has shown that antidepressants can increase the likelihood of suicidal tendencies for children, adolescents, and sometimes young adults. Therefore, individuals experiencing suicidal thoughts or who have engaged in suicidal behaviors are urged to inform their doctor and avoid using this drug.

Trazodone Can Be Addictive

Trazodone is not believed to be as habit-forming as other more potent depressants, such as opioids and benzodiazepines. However, this fact does not mean that at least an emotional addiction to trazodone cannot occur. Because it provides sedating effects, people can abuse trazodone for recreational purposes or as a daily sleep aid.

As with many psychoactive or intoxicating drugs, continuous use of this drug can lead to a condition known as tolerance, in which individuals will need to use increasingly higher doses to achieve the desired effects. In addition, once dependence sets in, it can cause unpleasant withdrawal symptoms when an individual tries to stop using the medicine.

Getting Addiction Treatment

Misusing or abusing trazodone for recreational purposes can lead to addiction and potentially overdose. Fortunately, for those addicted to trazodone, recovery is entirely possible. Just Believe Detox and Just Believe Recovery are specialized treatment centers that provide professional help for substance abuse, mental health conditions, and more.

Our programs include a wide variety of corrective methodologies and activities intended to address all aspects of an individual’s health and wellness, including psychotherapy, substance abuse education, group support, counseling, art and music therapy, and much, much more.

We Believe Recovery Is Possible For Everyone.
If you or a loved one need help with substance abuse and/or treatment, please contact Just Believe Recovery at (888) 380-0667. Our specialists can assess your individual needs and help you get the treatment that provides the best chance for long-term recovery.
⟹ Read This Next : Is Trazodone a Narcotic?
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